𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Human breast cancer cells induce angiogenesis, recruitment, and activation of osteoclasts in osteolytic metastasis

✍ Scribed by Bent Winding; Henriette Misander; Christina Sveigaard; Bente Therkildsen; Maria Jakobsen; Trine Overgaard; Merry Jo Oursler; Niels Tækker Foged

Publisher
Springer-Verlag
Year
2000
Tongue
English
Weight
454 KB
Volume
126
Category
Article
ISSN
1432-1335

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

Ipriflavone inhibits osteolytic bone met
Ipriflavone inhibits osteolytic bone metastasis of human breast cancer cells in a nude mouse model
✍ Teruo Iwasaki; Mutsuko Mukai; Tohru Tsujimura; Masaharu Tatsuta; Hiroyuki Nakamu 📂 Article 📅 2002 🏛 John Wiley and Sons 🌐 French ⚖ 274 KB

## Abstract Osteolytic bone metastasis is a frequent problem in the treatment of cancer. Ipriflavone, a synthetic isoflavone that inhibits osteoclastic bone resorption, has been used for the treatment of osteoporosis in some countries. Some other isoflavones also exhibit an antitumor effect __in vi

Targeted overexpression of BSP in osteoc
Targeted overexpression of BSP in osteoclasts promotes bone metastasis of breast cancer cells
✍ Qisheng Tu; Jin Zhang; Amanda Fix; Erika Brewer; Yi-Ping Li; Zhi-yuan Zhang; Jak 📂 Article 📅 2009 🏛 John Wiley and Sons 🌐 English ⚖ 782 KB

## Abstract Bone is one of the most common sites of breast cancer metastasis while bone sialoprotein (BSP) is thought to play an important role in bone metastasis of malignant tumors. The objective of this study is to determine the role of BSP overexpression in osteolytic metastasis using two homoz

Human breast cancer induces osteoclast a
Human breast cancer induces osteoclast activation and increases the number of osteoclasts at sites of tumor osteolysis
✍ Denis R Closhisy; Diane Palkert; Margaret L. R. Ramnaraine; Ilya Pekurovsky; Mer 📂 Article 📅 1996 🏛 Elsevier Science 🌐 English ⚖ 717 KB

## Abstract The cellular mechanism through which osseous breast cancer metastases induce the focal destruction of bone (tumor osteolysis) is unknown. An athymic mouse model designed for the study of tumor osteolysis was developed and the influence of two human breast cancer tumors on bone was studi

Protein C inhibitor inhibits breast canc
Protein C inhibitor inhibits breast cancer cell growth, metastasis and angiogenesis independently of its protease inhibitory activity
✍ Kunihiro Asanuma; Tomoaki Yoshikawa; Tatsuya Hayashi; Nobuyuki Akita; Norimi Nak 📂 Article 📅 2007 🏛 John Wiley and Sons 🌐 French ⚖ 739 KB

## Abstract Protein C inhibitor (PCI) regulates the anticoagulant protein C pathway and also inhibits urinary plasminogen activator (uPA), a mediator of tumor cell invasion. In the present study, we evaluated the effect of human PCI and its inactive derivatives on tumor growth and metastasis of hum

Tamoxifen induces TGF-β1 activity and ap
Tamoxifen induces TGF-β1 activity and apoptosis of human MCF-7 breast cancer cells in vitro
✍ Hongmin Chen; Thomas R. Tritton; Nicholas Kenny; Marlene Absher; Jen-Fu Chiu 📂 Article 📅 1996 🏛 John Wiley and Sons 🌐 English ⚖ 882 KB

We report here that the antiestrogen tamoxifen (TAM) induces cell death in human breast cancer cell line MCF-7. We assessed the type of cell death induced by TAM in this breast cancer cell line on the basis of morphological and biochemical characteristics. Dying cells showed morphological characteri