Human aryl hydrocarbon receptor nuclear translocator gene (ARNT) D/N511 polymorphism
โ Scribed by Henian Cao; Robert A. Hegele
- Publisher
- Nature Publishing Group
- Year
- 2000
- Tongue
- English
- Weight
- 100 KB
- Volume
- 45
- Category
- Article
- ISSN
- 1435-232X
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๐ SIMILAR VOLUMES
## Background: Androgen-dependent tissue has been reported to be affected by chemical ligands of the aryl hydrocarbon receptor (ahr), a ligand-activated transcription factor, which heterodimerizes with the aryl hydrocarbon receptor nuclear translocator protein (arnt). ## Methods: Fetal (n = 3), b
Rat CYP1A1 promoter-luciferase, transiently transfected wild-type and 4S PAH receptor (glycine N-methyl transferase, GNMT)-transformed Chinese hamster ovary (CHO) cells were exposed to benzo[a]pyrene and assayed for luciferase activity as an indicator of CYP1A1 promoter activity. CHO cells transform