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Human amyloid-β causes changes in the levels of endothelial protein kinase C and its α isoform in vitro

✍ Scribed by Magdolna Pakaski; Lajos Balaspiri; Frederic Checler; Peter Kasa

Book ID: 117409783
Publisher: Elsevier Science
Year: 2002
Tongue: English
Weight: 220 KB
Volume: 41
Category: Article
ISSN: 0197-0186
DOI: 10.1016/s0197-0186(02)00026-8

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## Abstract Previous studies have suggested that protein kinase C (PKC) may play an important role in colon carcinogenesis and that human colon tumors have less total PKC enzyme activity than normal tissue. Because PKC is a multigene family that enocodes for at least 11 distinct isofroms, in the st