๐”– Bobbio Scriptorium
โœฆ   LIBER   โœฆ

HTLV-I, Adult T-Cell leukemia, and tropical spastic paraparesis

โœ Scribed by P. S. Sarin

Publisher
John Wiley and Sons
Year
1988
Tongue
English
Weight
399 KB
Volume
23
Category
Article
ISSN
0364-5134

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โœฆ Synopsis

Human lymphotropic retroviruses have been identified as the etiological agents of adult T-cell leukemia and acquired immunodeficiency syndrome (AIDS). Human T-lymphotropic virus type I (HTLV-I) has been linked to the etiology of ATL, and human immunodeficiency virus type I (HIV-I) has been identified as the cause of AIDS. Both retroviruses are T-cell tropic. HTLV-I is a transforming virus, whereas HIV-I is a cytopathic virus and kills the cells it infects. HTLV-I has recently been identified from some patients with tropical spastic paraparesis, and it appears that HTLV-I infection alone or in the presence of other cofactors may be important in the development of this neurological dysfunction.

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