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HTLV-1 Gag protein associates with CD82 tetraspanin microdomains at the plasma membrane

✍ Scribed by Dmitriy Mazurov; Gisela Heidecker; David Derse


Book ID
113946638
Publisher
Elsevier Science
Year
2006
Tongue
English
Weight
498 KB
Volume
346
Category
Article
ISSN
0042-6822

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✍ Peter J.M. Stroeken; Belén Alvarez; Jacco van Rheenen; Yvonne M. Wijnands; Dirk 📂 Article 📅 2006 🏛 John Wiley and Sons 🌐 English ⚖ 436 KB

## Abstract The integrin cytoplasmic domain‐associated protein‐1 (ICAP‐1) binds via its C‐terminal PTB (phosphotyrosine‐binding) domain to the cytoplasmic tails of β1 but not other integrins. Using the yeast two‐hybrid assay, we found that ICAP‐1 binds the ROCK‐I kinase, an effector of the RhoA GTP