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HSV thymidine kinase gene therapy prolongs survival in malignant glioma

Book ID
120856562
Publisher
Adis International Limited (now part of Wolters Kluwer Health)
Year
2004
Weight
133 KB
Volume
&NA;
Category
Article
ISSN
1173-8324

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## Abstract ## Background The most extensively investigated strategy of suicide gene therapy for treatment of cancer is the transfer of the herpes simplex virus thymidine kinase (HSV‐TK) gene followed by administration of antiviral prodrugs such as acyclovir (ACV) and ganciclovir (GCV). The choice