HSP90 is a key for telomerase activation and malignant transition in pheochromocytoma
β Scribed by Carsten Boltze; Hendrik Lehnert; Regine Schneider-Stock; Brigitte Peters; Cuong Hoang-Vu; Albert Roessner
- Book ID
- 111637945
- Publisher
- Springer
- Year
- 2003
- Tongue
- English
- Weight
- 300 KB
- Volume
- 22
- Category
- Article
- ISSN
- 0969-711X
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## Abstract Telomerase activity (TA) and the expression of its enzymatic subunits, which have been demonstrated in many tumors, remain poorly investigated in tumors associated with neurofibromatosis type 1 (NF1). In this study, we analysed the association of TA and the expression of telomerase RNA
Mn 2Ψ treatment has been shown to promote neurite outgrowth in rat pheochromocytoma (PC12) cells in a time-and dose-dependent manner. This process is mediated through the interactions of extracellular matrix (ECM) proteins and integrin receptors. Studies were performed to determine whether the phosp