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HSP72 and gp96 in gastroenterological cancers

✍ Scribed by Wang, Xiaoping; Wang, Qiaoxia; Lin, Huanping; Li, Sanzhong; Sun, Lijun; Yang, Yixin


Book ID
125424153
Publisher
Elsevier Science
Year
2013
Tongue
English
Weight
216 KB
Volume
417
Category
Article
ISSN
0009-8981

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The heat shock proteins (HSP) gp96 and hsp70 have been shown to have a critical role in eliciting adaptive immune responses to cancers and viruses. This role derives from (i) their ability to chaperone antigenic peptides generated in the cells from which the HSP are isolated, and (ii) their capacity