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HSM2 (HMO1) gene participates in mutagenesis control in yeast Saccharomyces cerevisiae

✍ Scribed by S.Yu. Alekseev; S.V. Kovaltsova; I.V. Fedorova; L.M. Gracheva; T.A. Evstukhina; V.T. Peshekhonov; V.G. Korolev


Book ID
117798824
Publisher
Elsevier Science
Year
2002
Tongue
English
Weight
134 KB
Volume
1
Category
Article
ISSN
1568-7864

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HAM1, the gene controlling 6-N-hydroxyla
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The haml mutant of yeast Saccharomyces cerevisiae is sensitive to the mutagenic and lethal effects of the base analog, 6-N-hydroxylaminopurine (HAP). We have isolated a clone from a centromere-plasmid-based genomic library complementing HAP sensitivity of the haml strain. After subcloning, a 3.4 kb