✦ LIBER ✦

HSAB principle: Applications of its global and local forms in organic chemistry

✍ Scribed by P. Geerlings; F. De Proft

Publisher: John Wiley and Sons
Year: 2000
Tongue: English
Weight: 245 KB
Volume: 80
Category: Article
ISSN: 0020-7608
DOI: 10.1002/1097-461x(2000)80:2<227::aid-qua17>3.0.co;2-n

No coin nor oath required. For personal study only.

✦ Synopsis

The hard and soft acids and bases (HSAB) principle, both in its local and global versions, is applied, to a series of chemical reactions, including eleminations and substitutions, Diels-Alder cycloadditions, enolate-ion alkylation, and 1,3-dipolar additions. It will be shown that this principle, in the different resolutions, provides a powerful tool in the study of regioselectivity problems in organic chemistry.