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HPV Vaccines: Preclinical Development

✍ Scribed by Lutz Gissmann


Book ID
113467324
Publisher
Elsevier Science
Year
2009
Tongue
English
Weight
98 KB
Volume
40
Category
Article
ISSN
0188-4409

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To allow vaccination irrespective of HLA type, DNA vaccines encoding full-length antigens are required. However, here, we demonstrate that the immunogenicity of DNA vaccines encoding the full-length human papillomavirus (HPV) type 16 E7 and E6 proteins is highly reduced compared to vaccines encoding