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hprt mutation frequency among workers exposed to 1,3-butadiene in China

โœ Scribed by Richard B Hayes; Liqiang Xi; William E Bechtold; Nataniel Rothman; Ming Yao; Rogene Henderson; Luoping Zhang; Martyn T Smith; Dongpu Zhang; Joseph Wiemels; Mustafa Dosemeci; Songnian Yin; J.Patrick O'Neill


Publisher
Elsevier Science
Year
1996
Tongue
English
Weight
552 KB
Volume
113
Category
Article
ISSN
0300-483X

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Increased frequency of mutations at A:T
โœ Leslie Recio; Kathy G. Meyer ๐Ÿ“‚ Article ๐Ÿ“… 1995 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 676 KB

W e have examined the spectra of mutations in a collection of 7 4 lac1 mutants isolated from the bone marrow of B6C3F1 lac1 transgenic mice exposed to 1,250 ppm 1,3-butadiene (BD). Of the 49 inde pendent mutations analyzed in the present study, 30 of 49 (61 %) were point mutations at G:C base pairs,