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HPMA-oligolysine copolymers for gene delivery: Optimization of peptide length and polymer molecular weight

✍ Scribed by Russell N. Johnson; David S.H. Chu; Julie Shi; Joan G. Schellinger; Peter M. Carlson; Suzie H. Pun


Book ID
113694711
Publisher
Elsevier Science
Year
2011
Tongue
English
Weight
886 KB
Volume
155
Category
Article
ISSN
0168-3659

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## Abstract An ideal gene carrier is required both in safety and efficiency for transfection. Polyethylenimine (PEI), a well‐studied cationic polymer, has been proved with high transfection efficiency, but is reported as toxicity in many cell lines. In this study, PEI was coupled with polyethylene