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HPLC determination of methylphenidate and its metabolite, ritalinic acid, by high-performance liquid chromatography with peroxyoxalate chemiluminescence detection

✍ Scribed by Mitsuhiro Wada; Keisuke Abe; Rie Ikeda; Ruri Kikura-Hanajiri; Naotaka Kuroda; Kenichiro Nakashima

Publisher
Springer
Year
2011
Tongue
English
Weight
263 KB
Volume
400
Category
Article
ISSN
1618-2650

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## Methylphenidate (MP, Ritalin 1 ) is a psychotropic drug widely prescribed to children for treating the symptoms of attention deficit disorder with and without hyperactivity. Because little information exists about the effects of chronic MP administration on cognitive function in children, measur