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HPLC determination of estradiol, its degradation product, and preservatives in new topical formulation Estrogel HBF

✍ Scribed by Lucie Nováková; Petr Solich; Ludmila Matysová; Jan Šícha


Publisher
Springer
Year
2004
Tongue
English
Weight
330 KB
Volume
379
Category
Article
ISSN
1618-2650

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✍ Yuerong Rose Ye; Edin Bektic; Richard Buchta; Robert Houlden; Barry Hunt 📂 Article 📅 2004 🏛 John Wiley and Sons 🌐 English ⚖ 781 KB

## Abstract A new HPLC method based on reverse phase separation and photodiode‐array detection has been developed for the simultaneous determination of tretinoin and clindamycin phosphate, and their degradation products in topical formulations. The method has been shown to be stability indicating,