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HPLC and chemometric-assisted spectrophotometric methods for simultaneous determination of atenolol, amiloride hydrochloride and chlorthalidone

✍ Scribed by Alaa El-Gindy; Samy Emara; Ahmed Mostafa


Book ID
113619795
Publisher
Elsevier Science
Year
2005
Tongue
English
Weight
381 KB
Volume
60
Category
Article
ISSN
0014-827X

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HPLC method for the simultaneous determi
✍ Alaa El-Gindy; Shehab Sallam; Randa A. Abdel-Salam πŸ“‚ Article πŸ“… 2008 πŸ› John Wiley and Sons 🌐 English βš– 424 KB

## Abstract A high‐performance liquid chromatographic method was optimized and validated for the determination of atenolol and chlorthalidone (CT) in human breast milk. The milk samples were extracted and purified using ACN and phosphoric acid for precipitation of proteins followed by removal of AC