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HPLC Analysis and Pharmacokinetic Study of Paeoniflorin after Intravenous Administration of a New Frozen Dry Powder Formulation in Rats

✍ Scribed by Shan Cheng; Feng Qiu; Shuhui Wang; Junqi He

Book ID
111790522
Publisher
Springer
Year
2006
Tongue
English
Weight
264 KB
Volume
64
Category
Article
ISSN
0009-5893

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## Abstract Recently, as a new type of anti‐AIDS drug, an HIV‐1 protease inhibitor, KNI‐174, has been synthesized; it shows a potent and selective HIV‐1 protease inhibitory activity __in vitro__. In this study, we developed an HPLC assay system for KNI‐174 in rat plasma and examined the pharmacokin