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HP1 and the dynamics of heterochromatin maintenance

✍ Scribed by Maison, Christèle; Almouzni, Geneviève

Book ID
109958108
Publisher
Nature Publishing Group
Year
2004
Tongue
English
Weight
194 KB
Volume
5
Category
Article
ISSN
1471-0072

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## Abstract Heterochromatin domains are important for gene silencing, centromere organization, and genomic stability. These genomic domains are marked with specific histone modifications, heterochromatin protein 1 (HP1) binding and DNA methylation. The retinoblastoma tumor suppressor, RB mediates t