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How tumors might withstand γδ T-cell attack

✍ Scribed by Aude-Hélène Capietto; Ludovic Martinet; Jean-Jacques Fournié


Book ID
105759503
Publisher
Springer
Year
2011
Tongue
English
Weight
346 KB
Volume
68
Category
Article
ISSN
1420-682X

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Peripheral gammadelta T cells derived from healthy donors were found to exhibit cytotoxicity against a variety of tumor cell lines in vitro, including CNE2, which was established from nasopharyngeal carcinoma (NPC). The anti-tumor effects were further studied in a mouse model. Control nude mice inoc