How to assess the clinical impact of tre
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Helena Chmura Kraemer; Ellen Frank; David J. Kupfer
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Article
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2011
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John Wiley and Sons
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English
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While randomized clinical trials (RCTs) should provide the basis for evidence-based medicine, as currently designed and analyzed, they often mislead clinical decision-making. Comparative effectiveness evaluation of two treatments [Treatment 1 (T1) versus Treatment 2 (T2)] should not be determined by