𝔖 Bobbio Scriptorium
✦   LIBER   ✦

How good is the evidence for the lipid hypothesis?

✍ Scribed by John Stanley

Publisher
Wiley (John Wiley & Sons)
Year
2010
Tongue
English
Weight
550 KB
Volume
22
Category
Article
ISSN
0956-666X

No coin nor oath required. For personal study only.

✦ Synopsis

Abstract

The evidence for the lipid hypothesis is weak. After 20 years of follow‐up, the Nurses Health Study, a prospective cohort study, was no longer able to demonstrate an association between intakes of saturated fat and risk of developing coronary heart disease. Randomised controlled trials with statins have shown that lowering LDL‐cholesterol levels by 23% can reduce the risk of developing cardiovascular disease but reducing saturated fat can only reduce cholesterol levels by 10%. This issue can only be resolved by carrying out randomised controlled dietary trials with CVD endpoints. Although there are scientific difficulties standing in the way of such trials, it is the opinion of this author that these can be overcome. Whether there is the political will to fund them is another matter although some of the money currently spent on prospective cohort studies would be far better spent on randomised controlled trials.

πŸ“œ SIMILAR VOLUMES

How good is good agreement: Evaluating t
How good is good agreement: Evaluating the reliability of quantum-mechanically calculated observables
✍ Bernard J. Ransil πŸ“‚ Article πŸ“… 1980 πŸ› John Wiley and Sons 🌐 English βš– 639 KB

## Abstract The practical value of a wave function derives from its ability to estimate or predict the chemical and physical properties of the electronic structure which it describes. Reliability is defined as a property to be evaluated on the basis of (i) the magnitude of the difference between th

Here is the evidence, now what is the hy
Here is the evidence, now what is the hypothesis? The complementary roles of inductive and hypothesis-driven science in the post-genomic era
✍ Douglas B. Kell; Stephen G. Oliver πŸ“‚ Article πŸ“… 2003 πŸ› John Wiley and Sons 🌐 English βš– 104 KB πŸ‘ 3 views

## Abstract It is considered in some quarters that hypothesis‐driven methods are the only valuable, reliable or significant means of scientific advance. Data‐driven or β€˜inductive’ advances in scientific knowledge are then seen as marginal, irrelevant, insecure or wrong‐headed, while the development

cover
Good Vibes, Good Life How Self-Love Is the Key to Unlocking Your Greatness
✍ Vex King πŸ“‚ Fiction πŸ“… 2018 πŸ› Hay House 🌐 English βš– 267 KB πŸ‘ 1 views

**A beautifully designed book full of inspiring quotes and tried-and-tested wisdom on using positivity to create a life you love.** How can you learn to truly love yourself? How can you transform negative emotions into positive ones? Is it possible to find lasting happiness? In this book, Instag