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How fast is repopulation of tumor cells during the treatment gap?

✍ Scribed by Rafal Tarnawski; Jack Fowler; Krzysztof Skladowski; Andrzej Świerniak; Rafal Suwiński; Boguslaw Maciejewski; Andrzej Wygoda

Book ID
108434809
Publisher
Elsevier Science
Year
2002
Tongue
English
Weight
165 KB
Volume
54
Category
Article
ISSN
0360-3016

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## Abstract Genetic instability leads to tumor heterogeneity, which in turn provides a source of cell variants responsible for drug resistance. However, the source of resistant cells during the process of acquired resistance is poorly understood. Our aim has been to characterize the mechanism by wh