๐”– Bobbio Scriptorium
โœฆ   LIBER   โœฆ

How enzymes adapt: lessons from directed evolution

โœ Scribed by Frances H Arnold; Patrick L Wintrode; Kentaro Miyazaki; Anne Gershenson

Book ID
114326841
Publisher
Elsevier Science
Year
2001
Tongue
English
Weight
183 KB
Volume
26
Category
Article
ISSN
0968-0004

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## Abstract Estrogen synthesis evolved in chordates to control reproduction. The terminal enzyme in the cascade directly responsible for estrogen synthesis is aromatase cytochrome P450 (P450arom) encoded by the CYP19 gene. Mammals typically have a single CYP19 gene but pigs, peccaries and other Sui