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How does prolonged caloric restriction ameliorate age-related impairment of long-term potentiation in the hippocampus?

✍ Scribed by Mitsuko Okada; Hiroshi Nakanishi; Toshiaki Amamoto; Ryuji Urae; Susumu Ando; Kazuyoshi Yazawa; Michihiro Fujiwara


Book ID
117386154
Publisher
Elsevier Science
Year
2003
Tongue
English
Weight
337 KB
Volume
111
Category
Article
ISSN
0169-328X

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## Abstract Aging is associated with an impaired ability to maintain long‐term potentiation (LTP), but the underlying cause of the impairment remains unclear. To gain a better understanding of the cellular and molecular mechanisms responsible for this impairment, the synaptic transmission and plast