✦ LIBER ✦

Hot-topic debate on kidney function: Renal-sparing approaches are ineffective

✍ Scribed by John R. Lake

Book ID: 102470680
Publisher: John Wiley and Sons
Year: 2011
Tongue: English
Weight: 75 KB
Volume: 17
Category: Article
ISSN: 1527-6465
DOI: 10.1002/lt.22429

No coin nor oath required. For personal study only.

✦ Synopsis

Key Points

Both acute kidney injury and chronic renal disease are common in patients undergoing liver transplantation. The etiologies are mixed. 2. The incidence of chronic renal failure after liver transplantation is unacceptable, and it has a significant impact on long-term outcomes after liver transplantation.
The role of calcineurin inhibitors (CNIs) in the development of posttransplant chronic renal failure is likely overrated. 4. The use of CNIs in the early posttransplant period is currently essential. 5. Whether new agents will be able to provide effective immunosuppression as primary immunosuppressives remains to be proven.

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✍ François Durand 📂 Article 📅 2011 🏛 John Wiley and Sons 🌐 English ⚖ 104 KB

1. Renal function is frequently compromised in candidates for transplantation with advanced cirrhosis. These patients frequently have chronic and irreversible kidney changes at the time of transplantation. 2. The accumulated incidence of chronic renal failure is high in liver transplant recipients.