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Hot-spot mutations in hepatitis B virus X gene in hepatocellular carcinoma

✍ Scribed by Chu Chieh Hsia; Hao Yuwen; Edward Tabor


Book ID
118551926
Publisher
The Lancet
Year
1996
Tongue
English
Weight
42 KB
Volume
348
Category
Article
ISSN
0140-6736

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To explore the role of hepatitis B virus (HBV) X protein in liver carcinogenesis, independently from its role in viral replication, we have analyzed X gene structure and expression in tumorous and non-tumorous tissues obtained from 9 hepatitis B surface antigen (HBsAg)-negative, HBV DNApositive pati