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Host innate and Th1 responses and the bacterial factors that control Mycobacterium tuberculosis infection

โœ Scribed by Padmini Salgame


Book ID
108099500
Publisher
Elsevier Science
Year
2005
Tongue
English
Weight
391 KB
Volume
17
Category
Article
ISSN
0952-7915

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IL-10 regulates the balance of an immune response between pathogen clearance and immunopathology. We show here that __Mycobacterium tuberculosis__ (__Mtb__) infection in the absence of IL-10 (IL-10^โˆ’/โˆ’^ mice) results in reduced bacterial loads in the lung. This reduction was preceded by an accelerat