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Hormone replacement therapy and the risk of ovarian cancer in BRCA1 and BRCA2 mutation carriers

โœ Scribed by Joanne Kotsopoulos; Jan Lubinski; Susan L. Neuhausen; Henry T. Lynch; Barry Rosen; Peter Ainsworth; Pal Moller; Parviz Ghadirian; Claudine Isaacs; Beth Karlan; Ping Sun; Steven A. Narod


Book ID
113960170
Publisher
Elsevier Science
Year
2006
Tongue
English
Weight
100 KB
Volume
100
Category
Article
ISSN
0090-8258

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Germline mutations in BRCA1 and BRCA2 are associated with increased risks of breast and ovarian cancer. A genome-wide association study (GWAS) identified six alleles associated with risk of ovarian cancer for women in the general population. We evaluated four of these loci as potential modifiers of