✦ LIBER ✦

Hormone receptors in breast cancer: A conservative determination of receptors' presence in tissue and ipsilateral normal mammary gland

✍ Scribed by F. Badellino; G. Canavese; A. Catturich; G. Battistini; G. Amoretti; S. Bertoglio; F. Boccardo; M. Paganuzzi; G. Tanara

Publisher: John Wiley and Sons
Year: 1988
Tongue: English
Weight: 365 KB
Volume: 37
Category: Article
ISSN: 0022-4790
DOI: 10.1002/jso.2930370205

No coin nor oath required. For personal study only.

✦ Synopsis

Estrogen (ER) and progesterone (PgR) receptors were evaluated in the tumor tissue (T) and in the mammary gland far from malignancy (D) in 36 breast cancers. Results were correlated with the pathological grading of the tumor and the axillary nodal status. It is suggested that a lower cancer malignancy with negative nodes and lower values of pathological grading (Gl-G2) may be associated with a high level of ER in the mammary parenchyma far from the tumor (D).

📜 SIMILAR VOLUMES

Expression of the receptor for parathyro

Expression of the receptor for parathyroid hormone-related protein in normal and malignant breast tissue

✍ Downey, Sarah E.; Hoyland, Judith; Freemont, Anthony J.; Knox, Fiona; Walls, Jan 📂 Article 📅 1997 🏛 John Wiley and Sons 🌐 English ⚖ 294 KB 👁 2 views

Parathyroid hormone-related protein (PTHrP) is the cause of humoral hypercalcaemia of malignancy and interacts with parathyroid hormone (PTH) receptors. Breast cancer cells produce PTHrP in vitro and in vivo. The breast cancer cell line MCF-7, which products PTHrP and expresses PTHrP receptors, prol

Breast cancer incidence and estrogen rec

Breast cancer incidence and estrogen receptor α in normal mammary tissue—An epidemiologic study among Japanese women in Japan and Hawaii

✍ James S. Lawson; Andrew S. Field; Dinh D. Tran; Jeffrey Killeen; Gertraud Maskar 📂 Article 📅 2002 🏛 John Wiley and Sons 🌐 French ⚖ 78 KB

## Abstract We have undertaken a study to examine whether the difference in breast cancer incidence between 2 populations of similar genetic background is reflected in a similar pattern of estrogen receptor α expression in normal mammary gland. Study participants were 92 Japanese women from Sapporo

Characterization and modulation of a pro

Characterization and modulation of a prolactin receptor mRNA isoform in normal and tumoral human breast tissues

✍ Karine Laud; Isabelle Gourdou; Lucette Belair; Jean-Philippe Peyrat; Jean Djiane 📂 Article 📅 2000 🏛 John Wiley and Sons 🌐 French ⚖ 152 KB 👁 2 views

+331G/A variant in the progesterone rece

+331G/A variant in the progesterone receptor gene, postmenopausal hormone use and risk of breast cancer

✍ Joanne Kotsopoulos; Shelley S. Tworoger; Immaculata DeVivo; Susan E. Hankinson; 📂 Article 📅 2009 🏛 John Wiley and Sons 🌐 French ⚖ 103 KB 👁 2 views

## Abstract A functional promoter polymorphism in the progesterone receptor (__PR__) gene previously has been associated with an increased risk of postmenopausal breast cancer. Whether the relationship between genetic variation in __PR__ and risk of breast cancer is modified by postmenopausal hormo

Steroid-hormone receptors in nonpalpable

Steroid-hormone receptors in nonpalpable and more advanced stages of breast cancer. A contribution to the biology and natural history of carcinoma of the female breast

✍ J. G. M. Tinnemans; L. V. A. M. Beex; Th. Wobbes; R. F. Sluis; J. M. M. Raemaeke 📂 Article 📅 1990 🏛 John Wiley and Sons 🌐 English ⚖ 336 KB 👁 2 views

Identification and characterization of a

Identification and characterization of a negative regulatory element within the epidermal growth factor receptor gene first intron in hormone-dependent breast cancer cells

✍ Melissa A. Wilson; Susan A. Chrysogelos 📂 Article 📅 2002 🏛 John Wiley and Sons 🌐 English ⚖ 198 KB

## Abstract The epidermal growth factor receptor (EGFR) exhibits an inverse correlation with estrogen receptor (ER) expression in the majority of breast cancers, predicting a poor response to endocrine therapy and poor survival rate. Inappropriate overexpression of EGFR in breast cancer is associat