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Hormone controlled phosphorylation and degradation of CYP2B1 and CYP2E1 in isolated rat hepatocytes

✍ Scribed by Inger Johansson; Erik Eliasson; Magnus Ingelman-Sundberg

Book ID
115763924
Publisher
Elsevier Science
Year
1991
Tongue
English
Weight
545 KB
Volume
174
Category
Article
ISSN
0006-291X

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## Abstract We report a comprehensive examination of rat hepatic CYP1A2 and CYP2E1 ontogeny. We compare the data to human data to determine the rat's capacity as a model to identify CYP‐mediated mechanisms underlying age‐dependent differences in susceptibility to toxicity. We evaluated CYP expressi