Hormone- and dose schedule-dependent protection by HI-6 against soman and tabun poisoning

Efficacy of a combination of acetylcholi

Efficacy of a combination of acetylcholinesterase reactivators, HI-6 and obidoxime, against tabun and soman poisoning of mice

✍ John G. Clement; J. Deborah Shiloff; Chris Gennings 📂 Article 📅 1987 🏛 Springer-Verlag 🌐 English ⚖ 582 KB

The bispyridinium oxime HI-6, 1-((((4-amino-carbonyl)pyridinio)methoxy) methyl)-2-(hydroxyimino)methyl)pyridinium dichloride monohydrate, combined with atropine is an effective treatment for soman (pinacolyl methylphosphonofluoridate) poisoning but is relatively ineffective against tabun (ethyl N-di