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Hormonal Regulation of Stearoyl Coenzyme-A Desaturase 1 Activity and Gene Expression in Primary Cultures of Chicken Hepatocytes

โœ Scribed by Pascal Lefevre; Christian Diot; Philippe Legrand; Madeleine Douaire

Book ID
115567730
Publisher
Elsevier Science
Year
1999
Tongue
English
Weight
275 KB
Volume
368
Category
Article
ISSN
0003-9861

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## Abstract The culture of fetal hepatocytes for 64 h in medium supplemented with 5 mM glucose, T3, insulin, and dexamethasone resulted in the coordinate precocious expression of malic enzyme mRNA, protein, and specific activity. T3 was the main inducer; meanwhile, insulin exerted a small synergist