Hoogsteen-Paired Homopurine [RP-PS]-DNA and Homopyrimidine RNA Strands Form a Thermally Stable Parallel Duplex

Homopurine and homopyrimidine strands co

Homopurine and homopyrimidine strands complementary in parallel orientation form an antiparallel duplex at neutral pH with A-C, G-T, and T-C mismatched base pairs

✍ Sukesh R. Bhaumik; Kandala V. R. Chary; Girjesh Govil; Keliang Liu; H. Todd Mile 📂 Article 📅 1997 🏛 Wiley (John Wiley & Sons) 🌐 English ⚖ 185 KB 👁 2 views

DNA sequences d-TGAGGAAAGAAGGT (a 14-mer) and d-CTCCTTTCTTCC (a 12-mer) are complementary in parallel orientation forming either Donohue (reverse Watson-Crick) base pairing at neutral pH or Hoogsteen base pairing at slightly acidic pH. The structure of the complex formed by dissolving the two strand