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Honokiol induces cytotoxic and cytostatic effects in malignant melanoma cancer cells

✍ Scribed by Gaurav Kaushik; Satish Ramalingam; Dharmalingam Subramaniam; Parthasarthy Rangarajan; Piero Protti; Prabhu Rammamoorthy; Shrikant Anant; Joshua M.V. Mammen


Book ID
119188023
Publisher
Elsevier Science
Year
2012
Tongue
English
Weight
788 KB
Volume
204
Category
Article
ISSN
0002-9610

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✍ K. K. Wary; R. N. Sharan πŸ“‚ Article πŸ“… 1991 πŸ› John Wiley and Sons 🌐 French βš– 488 KB πŸ‘ 1 views

Arecoline, an active alkaloid of Areca catechu L., and sodium nitrite, a food additive, are highly cytotoxic and cytostatic on the Hep 2 cell line when administered in an acidic environment (pH 4.2) in the presence of S-9 mixture. Hep 2 cells (10(6)) were treated with either 0.145, 0.725 or 1.449 mM