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Honokiol: an effective inhibitor of tumor necrosis factor- -induced up-regulation of inflammatory cytokine and chemokine production in human synovial fibroblasts

✍ Scribed by Li, J.; Shao, X.; Wu, L.; Feng, T.; Jin, C.; Fang, M.; Wu, N.; Yao, H.

Book ID: 125494875
Publisher: John Wiley and Sons
Year: 2011
Tongue: English
Weight: 228 KB
Volume: 43
Category: Article
ISSN: 1672-9145
DOI: 10.1093/abbs/gmr027

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## Objective: To investigate the effects of the antiinflammatory cytokines interleukin-4 (il-4), il-10, and il-13 on tumor necrosis factor alpha (tnfalpha)-induced prostaglandin e2 (pge2) release in the cellular signaling cascade on human osteoarthritis (oa) synovial fibroblasts. ## Methods: Huma