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Homozygous protein C deficiency in 3 unrelated adults

✍ Scribed by J. Conard; S. Poort; M.H. Horellou; P.H. Reitsma; R.M. Bertina; M. Samama


Book ID
119038973
Publisher
Elsevier Science
Year
1992
Tongue
English
Weight
77 KB
Volume
65
Category
Article
ISSN
0049-3848

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Homozygous protein C (PC) deficiency is a rare genetic defect that usually results in fatal thrombotic complications (purpura fulminans and DIC), but it can be successfully managed with oral anticoagulants or PC replacement. The successful use of PC replacement for two individuals is described. The