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Homozygous mouse embryos produced by microsurgery

✍ Scribed by Markert, Clement L. ;Petters, Robert M.

Publisher
John Wiley and Sons
Year
1977
Tongue
English
Weight
460 KB
Volume
201
Category
Article
ISSN
0022-104X

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✦ Synopsis

Abstract

Homozygous mouse blastocysts have been produced following microsurgical removal of one pronucleus from the fertilized egg, diploidization in cytochalasin B, and culture in vitro. This combination of techniques should greatly shorten the time required to obtain homozygous strains of mice.

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