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Homozygous disruption of the tip60 gene causes early embryonic lethality

โœ Scribed by Yaofei Hu; Joseph B. Fisher; Stacy Koprowski; Donna McAllister; Min-Su Kim; John Lough

Book ID
102818123
Publisher
John Wiley and Sons
Year
2009
Tongue
English
Weight
581 KB
Volume
238
Category
Article
ISSN
1058-8388

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Gene trapping with the retroviral ROSA โคgeo vector was used to generate lines of mice carrying disrupted genes. Both cDNA and genomic flanks have been cloned from a number of these lines. One mutation has been shown to disrupt the โฃ-enolase gene by insertion of the splice-trap vector into the first