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Homozygous deletion of the PTEN tumor-suppressor gene is not a feature in oral squamous cell carcinoma

✍ Scribed by Q Chen; L.P Samaranayake; H Zhou; L Xiao

Book ID: 114394404
Publisher: Elsevier Science
Year: 2000
Tongue: English
Weight: 132 KB
Volume: 36
Category: Article
ISSN: 1368-8375
DOI: 10.1016/s1368-8375(99)00068-8

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## Abstract Oral squamous cell carcinoma (OSCC) is the most common malignant neoplasm of the oral cavity, representing ˜90% of all oral carcinomas and accounting for 3–5% of all malignancies. The __WWOX__ gene (WW‐domain containing oxidoreductase) is a candidate tumor suppressor gene located at 16q

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