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Homology modeling of the structure of tobacco acetohydroxy acid synthase and examination of the active site by site-directed mutagenesis

✍ Scribed by Dung Tien Le; Moon-Young Yoon; Young Tae Kim; Jung-Do Choi

Book ID
116288242
Publisher
Elsevier Science
Year
2004
Tongue
English
Weight
553 KB
Volume
317
Category
Article
ISSN
0006-291X

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The structure of serine hydroxymethyltra
The structure of serine hydroxymethyltransferase as modeled by homology and validated by site-directed mutagenesis
✍ Stefano Pascarella; Sebastiana Angelaccio; Roberto Contestabile; Sonia Delle Fra πŸ“‚ Article πŸ“… 1998 πŸ› Cold Spring Harbor Laboratory Press 🌐 English βš– 759 KB

## Abstract We describe a model for the three‐dimensional structure of __E. coli__ serine hydroxymethyltransferase based on its sequence homology with other PLP enzymes of theα‐family and whose tertiary structures are known. The model suggests that certain amino acid residues at the putative active