Homology Modeling and Molecular Dynamics Simulations of the Mu Opioid Receptor in a Membrane–Aqueous System

On the structure and activity of membran

On the structure and activity of membrane receptors: A computational simulation of ligand-triggered activation in a model 5-HT1A receptor

✍ Leonardo Pardo; Harel Weinstein 📂 Article 📅 1997 🏛 John Wiley and Sons 🌐 English ⚖ 337 KB 👁 2 views

The relation between receptor structure and the mechanism by which ligands with different pharmacological efficacy elicit a response is analyzed in a three-dimensional w Ž .x molecular model of the human 5-HT receptor Pardo et al., J. Biomed. Sci. 3, 98 1996 . ## 1A According to the model, the ma