Correction of mutant Fanconi anemia gene
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Kittiphong Paiboonsukwong; Fumi Ohbayashi; Haruka Shiiba; Emi Aizawa; Takayuki Y
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Article
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2009
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John Wiley and Sons
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English
β 288 KB
## Abstract ## Background Adenoβassociated virus (AAV) vectors have been shown to correct a variety of mutations in human cells by homologous recombination (HR) at high rates, which can overcome insertional mutagenesis and transgene silencing, two of the major hurdles in conventional gene addition