Homogeneous Hydrogenation

✍ Scribed by Penny A. Chaloner, Miguel A. Esteruelas, Ferenc Joó, Luis A. Oro (auth.)

• Publisher: Springer Netherlands
• Year: 1994
• Tongue: English
• Leaves: 293
• Series: Catalysis by Metal Complexes 15
• Edition: 1
• Category: Library

✦ Synopsis

Homogeneous hydrogenation is one of the most thoroughly studied fields of homogeneous catalysis. The results of these studies have proved to be most important for an understanding of the underlying principles of the activation of small molecules by transition metal complexes. During the past three decades homogeneous hydrogenation has found widespread application in organic chemistry, including the production of important pharmaceuticals, especially where a sophisticated degree of selectivity is required.
This volume presents a general account of the main principles and applications of homogeneous hydrogenation by transition metal complexes. Special attention is devoted to the mechanisms by which these processes occur, and the role of the recently discovered complexes of molecular hydrogen is described. Sources of hydrogen, other than H₂, are also considered (transfer hydrogenation). The latest achievements in highly stereoselective hydrogenations have made possible many new applications in organic synthesis. These applications are documented by giving details of the reduction of important unsaturated substrates (alkenes, alkynes, aldehydes and ketones, nitrocompounds, etc.). Hydrogenation in biphasic and phase transfer catalyzed systems is also described. Finally, a discussion of the biochemical routes of H₂ activation highlights the similarities and differences in performing hydrogenation in both natural and synthetic systems.
For researchers working in the fields of homogeneous catalysis, especially in areas such as pharmaceuticals, plastics and fine chemicals.

✦ Table of Contents

Front Matter....Pages i-x
Introduction....Pages 1-3
The Mechanisms of Homogeneous Hydrogenation....Pages 5-85
Homogeneous Transfer Hydrogenation Catalysed by Metal Complexes....Pages 87-118
Homogeneous Hydrogenation in Organic Synthesis....Pages 119-181
Hydrogenation in Aqueous Systems....Pages 183-239
Supported Metal Complexes....Pages 241-253
Hydrogen Activation in Biological Systems....Pages 255-270
Back Matter....Pages 271-289

✦ Subjects

Catalysis; Physical Chemistry; Industrial Chemistry/Chemical Engineering; Organic Chemistry