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“Homing to Niche,” a New Criterion for Hematopoietic Stem Cells?

✍ Scribed by Hideo Ema; Hiromitsu Nakauchi

Book ID: 117723499
Publisher: Elsevier Science
Year: 2004
Tongue: English
Weight: 41 KB
Volume: 20
Category: Article
ISSN: 1074-7613
DOI: 10.1016/s1074-7613(04)00002-0

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## Abstract The enormous regenerative capacity of the blood system to sustain functionally mature cells are generated from highly proliferative, short‐lived progenitors, which in turn arise from a rare population of pluripotent and self‐renewing hematopoietic stem cells (HSC). In the bone marrow, t