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Homing of lin−/CD117+ hematopoietic stem cells

✍ Scribed by Stanislav Filip; Jaroslav Mokrý; Jiřina Vávrová; Dana Čížková; Zuzana Šinkorová; Vlasta Tošnerová; Milan Bláha

Book ID
116928858
Publisher
Elsevier Science
Year
2009
Tongue
English
Weight
455 KB
Volume
41
Category
Article
ISSN
1473-0502

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✍ CHERYL L. HARDY; GAIL C. MEGASON 📂 Article 📅 1996 🏛 John Wiley and Sons 🌐 English ⚖ 882 KB

Homing of hematopoietic stem cells (HSC) may be defined as the cells' ability to seek marrow stroma selectively, to interact with it and subsequently to lodge within it to initiate hematopoiesis. This complex process is no doubt mediated through multiple recognition/adhesion events. Homing may proce