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Homeostasis and function of regulatory T cells (Tregs) in vivo : lessons from TCR-transgenic Tregs

✍ Scribed by Attridge, Kesley; Walker, Lucy S. K.


Book ID
121746755
Publisher
John Wiley and Sons
Year
2014
Tongue
English
Weight
326 KB
Volume
259
Category
Article
ISSN
0105-2896

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## Abstract The aim of this study was to investigate whether depletion of CD4^+^CD25^+^ regulatory T cells (Treg) from melanoma patients affects immune responses against tumors. By application of recombinant IL‐2‐diphteria toxin fusion protein, also known as ONTAK, we were able to significantly red