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Holothurins B 2 , B 3 , and B 4 , New Triterpene Glycosides from Mediterranean Sea Cucumbers of the Genus Holothuria

โœ Scribed by Silchenko, Alexandra S.; Stonik, Valentin A.; Avilov, Sergey A.; Kalinin, Vladimir I.; Kalinovsky, Anatoly I.; Zaharenko, Alexandr M.; Smirnov, Alexey V.; Mollo, Ernesto; Cimino, Guido


Book ID
121290311
Publisher
American Chemical Society
Year
2005
Tongue
English
Weight
83 KB
Volume
68
Category
Article
ISSN
0163-3864

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Two new sulfated triterpene glycosides, philinopsides A (1) and B (2), were isolated from the sea cucumber Pentacta quadrangularis. Their structures were established by extensive spectral analysis (2D-NMR and MS) and chemical evidence. Philinopside A (1) and B (2) showed significant cytotoxicity (ED