Holographic QSAR of Benzodiazepines
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David A. Winkler; Frank R. Burden
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Article
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1998
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Wiley (John Wiley & Sons)
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English
โ 139 KB
We have used a new molecular representation, the molecular hologram, to generate QSAR models for a set of benzodiazepines active at the GABA A receptor. This new representation is shown to yield superior structureactivity models than traditional physicochemical representations and other fragment-bas