This study demonstrates that cyclic AMP (cAMP) production is induced by lipopolysaccharide (LPS) stimulation and activates two different pathways in murine BV2 microglial cells. Two principal effector proteins for cAMP are protein kinase A (PKA) and cAMP-responsive guanine nucleotide exchange factor
β¦ LIBER β¦
HOIL-1 is not required for iron-mediated IRP2 degradation in HEK293 cells
β Scribed by Kimberly B. Zumbrennen; Eric S. Hanson; Elizabeth A. Leibold
- Book ID
- 113486097
- Publisher
- Elsevier Science
- Year
- 2008
- Tongue
- English
- Weight
- 981 KB
- Volume
- 1783
- Category
- Article
- ISSN
- 0167-4889
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## Abstract We are interested in determining the signaling pathways for 1,25βdihydroxyvitamin D~3~ (1,25D)βinduced differentiation of HL60 leukemic cells. One possible candidate is Rafβ1, which is known to signal cell proliferation and neoplastic transformation through MEK, ERK, and downstream targ