Hoechst 33258 Selectively Inhibits Group I Intron Self-Splicing by Affecting RNA Folding

New approaches to targeting RNA with oli

New approaches to targeting RNA with oligonucleotides: Inhibition of group I intron self-splicing

✍ Matthew D. Disney; Jessica L. Childs; Douglas H. Turner 📂 Article 📅 2003 🏛 Wiley (John Wiley & Sons) 🌐 English ⚖ 510 KB

## Abstract RNA is one class of relatively unexplored drug targets. Since RNAs play a myriad of essential roles, it is likely that new drugs can be developed that target RNA. There are several factors that make targeting RNA particularly attractive. First, the amount of information about the roles